Functional foods
Studying bioactive food components, proteins and peptides, and their potential applications in nutrition.
University of Calcutta Kolkata, India
Exploring functional foods and lipid nanotechnology at the Laboratory of Food Science and Technology.
Explore our researchOur work brings food science and nutrition together to investigate the properties and potential of food-derived materials.
Explore the departmentStudying bioactive food components, proteins and peptides, and their potential applications in nutrition.
Exploring lipid formulations and nanoemulsions for the delivery and study of bioactive compounds.
Investigating useful ingredients from food and oil-industry materials, including plant proteins and dietary fibres.
Prof. Pubali Dhar’s contributions connect lipid biotechnology, nano-nutrition and sustainable food resources.
Her research examines functional lipids and food-derived materials, with an emphasis on nutrient delivery, metabolic health and the use of agro-industrial by-products.
Research on unconventional vegetable seed oils and marine resources explores their role in chronic metabolic disorders. Studies of conjugated linolenic acids (CLnA) from bitter gourd seed oil investigate mechanisms related to glucose regulation, inflammation and cholesterol metabolism.
Work on lutein, sesame lignans, plant sterols and diacylglycerol (DAG) cooking oils examines nutritional regulation, obesity, leptin dynamics and macronutrient absorption.
To address limited bioavailability, chemical instability and autooxidation, the laboratory studies oil-in-water nanoemulsions and nanohydrogels using food-grade materials, including mustard and sesame protein isolates and phospholipids.
Studies of omega-3 fatty acid and sesame oil nano-formulations use experimental and flow-cytometric approaches to investigate cellular uptake, gastrointestinal bioaccessibility and mucosal barrier protection against foodborne pathogens. Further research explores potential applications in protein-energy malnutrition and gut-mucosal nutrient delivery for critically ill patients.
The laboratory’s waste-to-wealth research investigates agro-industrial by-products as resources for useful food and biomaterial ingredients. Work with the oleaginous yeast Starmerella bombicola explores the conversion of refinery waste into sophorolipid biosurfactants.
Research on biogenic silver nanoparticles and green biopolymer films examines potential antimicrobial, food-preservation and active-packaging applications, including shelf-life stability.
Ongoing work investigates growth, phenotypic plasticity and adaptive virulence in foodborne pathogens under simulated microgravity. This research seeks to inform future dietary interventions and food-preservation protocols for long-duration spaceflight and planetary missions.
Prof. Dhar contributes to curriculum development through membership of university Boards of Studies. Her academic and research interests connect nutritional science with molecular approaches and the development of nano-nutraceutical delivery systems.
Studies in food science, nutrition and nutraceutical delivery.
Principal investigator: Prof. Pubali Dhar
UGC Minor Research Project · 2002–2004
Studies on the protective role of dietary conjugated and non-conjugated polyunsaturated fatty acids (PUFAs) against coronary heart disease and diabetes mellitus.
The project compared the anti-inflammatory and antioxidant effects of conjugated alpha-eleostearic acid (α-ESA) with non-conjugated PUFAs. It examined the nutritional importance of conjugated linolenic acid (CLnA) in bitter gourd oil, contributing to knowledge in nutritional science.
UGC Minor Research Project · 2006–2008
Studies on the antioxidative effects of polyphenols present in some vegetables in the presence of pesticides.
The project investigated how pesticide exposure affects vegetable polyphenol content and antioxidant potential, and examined the relationship between polyphenol content and antioxidant efficiency.
Its public-education aim was to improve awareness of polyphenol-rich vegetables and their potential role in protecting against oxidative stress associated with pesticide exposure.
Nano Research Centre, University of Calcutta · 2009–2011
Formulation and development of nanoemulsion.
The project explored nanoemulsion technology to improve the solubility, absorption and bioavailability of poorly water-soluble nutraceuticals. It also considered opportunities for commercialisation, product innovation and value-added formulations with market potential.
UGC Major Research Project · 2010–2012
Studies on the antioxidative and antimicrobial activity of some edible flower extracts.
The project investigated the potential health-promoting properties of edible flowers of India, aiming to provide scientific evidence on their nutritional and medicinal value for nutritionists.
ICMR Research Project · 2011–2014
Studies on the antioxidative and immunomodulatory effects of conjugated linolenic acid (CLnA) from bitter gourd oil.
The project examined dose-dependent modulation of immune responses, including immune-cell activity and cytokine production. Its findings provided reference material for researchers in nutrition, biochemistry and immunology.
UPE Project · 2011–2013
Diet and nutrition status of lactating mothers belonging to different socioeconomic classes residing in rural parts of Hooghly district, and their probable correlation with milk lipid profiles.
The study examined the relationship between maternal nutritional intake and breast-milk lipid profiles among Bengali mothers. It aimed to inform maternal and child health awareness and support public health policy.
2012–2015
Supported by the Directorate of Vanaspati and Vegetable Oils and Fats, Ministry of Consumer Affairs, Government of India.
Studies on the antihypertensive and hypocholesterolemic effects of sesame seed protein.
The project investigated specific peptides or protein fractions associated with blood-pressure and cholesterol-lowering activities. Its outreach aim was to educate communities, healthcare professionals and nutritionists about the role of plant proteins in cardiovascular health.
UGC-DAE Consortium · 2016–2019
Application of green technology for the fabrication of biogenic flavonoid-coated silver nanoparticles.
The project investigated nanoparticle synthesis and potential applications in drug delivery, wound healing, antimicrobial formulations, biosensors and therapeutic products. Its focus included antimicrobial and antioxidant properties relevant to future infection-control and healthcare strategies.
UPE-II · 2017–2020
Engineering PUFA-rich nanoemulsion systems for critical nutritional therapy.
The project focused on controlled and targeted nutrient release, with the aim of improving nutrient delivery in critical care nutrition.
ICMR · 2019–2022
Systematizing novel lipid formulations as nanocarriers in targeting the molecular axis of hypersensitivity: For translational research.
The project investigated novel lipid-based nanocarriers with the aim of improving therapeutic efficacy. Its findings may inform further preclinical and clinical investigations into nanocarrier-based interventions for hypersensitivity disorders.
International Research Partnership, University of Saskatchewan, Canada · 2019–2022
Development of nutrient-rich oil-in-water nanoemulsion for diarrhoeal disease and associated malnutrition management in developing nations.
The project aimed to improve nutrient delivery and bioavailability to support the management of diarrhoeal disease and associated malnutrition. The developed system was explored for its potential to address nutrient deficiencies and improve nutritional status among vulnerable populations, especially children.
ICMR · 2022–2025
Identification and generation of immunomodulatory peptides from sesame seed oil meal: A novel radical approach in food value addition.
The project investigated the valorisation of sesame seed oil meal through the generation of bioactive peptides and examined their effects on immune-cell responses and cytokine activity. Its findings may support awareness of bioactive peptides and their potential role in immune health and preventive nutrition.
Ministry of AYUSH · 2023–2026
Effect of ghee from indigenous cow milk on cognition and neuroprotection against Alzheimer’s disease.
The project investigates the potential neuroprotective effects of ghee prepared from indigenous cow milk using Ayurvedic methods, focusing on neurodegeneration and neuronal damage associated with Alzheimer’s disease. The research explores whether traditional dietary fats could inform future nutritional strategies for age-related cognitive decline.
Palm Oil Council and OTAI · 2025–2026
Neurogastronomy insights: Comparing the effects of palm oil and alternative cooking oils on flavour perception and carcinogenic precursor formation.
The project examines interactions between food chemistry, sensory science and the neural processing of flavour. It aims to identify cooking-oil alternatives that combine desirable flavour with reduced formation of potentially harmful thermal degradation products, and to inform safer culinary practices.
Research is a shared pursuit. Meet the principal investigator and the scholars working in the laboratory.
Principal investigator
Professor, Department of Home Science
University of Calcutta
Prof. Dhar leads research in functional foods and lipid nanotechnology. She is also associated with the Centre for Research in Nanoscience and Nanotechnology.
Read the university profileGuided by Prof. Pubali Dhar · University of Calcutta
Dr. Rupali Dhara Mitra · 2011
Production and Nutritional Evaluation of Vegetable Oil-based Nutraceuticals
Dr. Sugata Bhattacharyya · 2012
Studies on the Biochemical Aspects of Marigold Flowers
Dr. Bidisa Mallik · 2013
Studies on the Antioxidative Status of Polyphenols Present in Some Leafy Vegetables
Dr. Sanjukta Dutta · 2013
Studies on the Antioxidative Effect of Polyphenols Isolated from Vegetables in Presence of Pesticides
Dr. Angira Das · 2015
Studies of Physicochemical Characteristics of Some Honeys from West Bengal, India
Dr. Sayani Mukerjee · 2015
Studies on the Antioxidative and Antimicrobial Effect of Oxalis corniculata Extracts
Dr. Ratna China · 2016
Studies on Antioxidative and Antimicrobial Activity of Some Edible Flower Extracts
Dr. Tanmoy Kumar Dey · 2016
Formulation of Functional Food Emulsions and Their In Vivo Studies
Dr. Debojyoti Paul · 2017
Studies of Prophylactic and Therapeutic Avenues of Conjugated Linolenic Acid Rich Oil Formulations
Dr. Roshni Chatterjee · 2018
Exploring the Therapeutic Benefits of Underutilized Unconventional Food Component
Dr. Ankhi Haldar · 2019
Studies on the Biochemical Aspects of the Edible Bivalve Lamellidens marginalis Available in West Bengal
Dr. Shaswati Das · 2024
Deciphering the Role of Black Seed Oil and Its Nanoparticle in Averting Breast Cancer Migration and Fostering Apoptosis
Dr. Amrita Chakraborty · 2024
Fabrication, Characterization and Evaluation of Bioactivity of Oil-in-Water Nanoemulsion
Dr. Arpita Banerjee · 2024
Studies on the Functional Properties of Enzymatically Extracted Dietary Fibres from Oil Seed Meals
Dr. Madhushrita Das · 2024
Studies on Application of Nanotechnology in the Preparation and Utilisation of Functional Food Ingredients and Food Products
Dr. Banerjee completed her PhD at the Laboratory of Food Science and Technology, University of Calcutta. She is currently Head of the Department of Food and Nutrition at Sister Nivedita University, Kolkata.

Dr. Chakraborty completed her PhD in Physiology at the Laboratory of Food Science and Technology, University of Calcutta. She is currently an Assistant Professor in the West Bengal Educational Service.

Dr. Das completed her PhD in Nanoscience and Nanotechnology at the Laboratory of Food Science and Technology, University of Calcutta. She is currently an Assistant Professor in the Department of Biotechnology at Techno India University.

Dr. Das completed her PhD in Nanoscience and Nanotechnology at the Laboratory of Food Science and Technology, University of Calcutta. She currently works in the corporate sector in Bangalore.

Sophorolipids: Sustainable Biosurfactants for Next-Generation Applications
Niloy Chatterjee, Srija Pal and Pubali Dhar. Lipid Industrial Handbook, 1st edition. Oil Technologists’ Association of India, 2025.
Bittergourd oil for optimal health
Pubali Dhar. Lipid Industrial Handbook, 1st edition. Oil Technologists’ Association of India, 2025.
Biodegradable Waste Products as Reducing Agents for Green Nanomaterial Synthesis and their Applications
Niloy Chatterjee and Pubali Dhar. Sustainable Green Synthesised Nano-Dimensional Materials for Energy and Environmental Applications. CRC Press, 2024.
The Future of Green Biopolymers in Packaging Applications DOI
Niloy Chatterjee, Sourav Kumar Nandi and Pubali Dhar. Green Biopolymers for Packaging Applications. CRC Press, 2025.
Green Biopolymers for Packaging: An Overview DOI
Niloy Chatterjee and Pubali Dhar. Green Biopolymers for Packaging Applications, 1st edition. CRC Press, 2025.
Low-Dimensional Biosensors for Global Challenges DOI
Niloy Chatterjee, Srija Pal and Pubali Dhar. Evolution of Low-Dimensional Biosensors in Food Safety, Agriculture, and Healthcare. CRC Press, 2026.
Low-Dimensional Biosensors for Environmental Monitoring DOI
Niloy Chatterjee, Debarchan Mondal and Pubali Dhar. Evolution of Low-Dimensional Biosensors in Food Safety, Agriculture, and Healthcare. CRC Press, 2026.
Phospholipid-Based Nanoplatforms
Amrita Chakraborty and Pubali Dhar. Handbook of Nanotechnology in Nutraceuticals. CRC Press.
Bio-nanocomposites: curse or miracle for the society? DOI
Niloy Chatterjee and Pubali Dhar. Characterization Techniques in Bionanocomposites: Advances, Challenges, and Applications. Woodhead Publishing, 2024.
Association Between Dietary Components and Autoimmune Diseases: Case Study DOI
Payal Das and Pubali Dhar. Nutrition Controversies and Advances in Autoimmune Disease (2 volumes). IGI Global, 2024.
Emerging Trends in Nutraceutical Research: Role of Minerals DOI
Singh, S. et al. Functional Foods and Nutraceuticals: Chemistry, Health Benefits and the Way Forward. Springer, Cham, 2024.
Functional and Bioactive Lipid Mediators in Modulating CVD Precursors
Debjyoti Paul, Tanmoy Kumar Dey, Amrita Chakraborty and Pubali Dhar. Functional Foods in Chronic Diseases, Volume 2. CreateSpace Independent Publishing Platform, USA.
Nanoformulation and administration of PUFA-rich systems for applications in modern healthcare
Debjyoti Paul, Tanmoy Kumar Dey and Pubali Dhar. Nanostructures for Novel Therapy: Synthesis, Characterization and Applications. Elsevier.
Promising functional lipids for therapeutic applications
Debjyoti Paul, Tanmoy Kumar Dey, Amrita Chakraborty and Pubali Dhar. Role of Material Science in Food Bioengineering. Elsevier.
Bioactivity of Nano-sized Nutraceuticals Against Cancer
Pubali Dhar. Functional Foods and Cancer: Bioactive Compounds and Cancer, Volume 4, 1st edition (Functional Food Science). Functional Food Centre Press.
Nanoceuticals: Mystifying Composites at the Interface of Nutrition, Medicine, and Technology
Niloy Chatterjee and Pubali Dhar. Handbook of Nanotechnology in Nutraceuticals. CRC Press, 2023.
Biotechnology: A dream or a nightmare
Pubali Dhar. Disaster and Its Management: Perspective and Future Approaches. ABC Publications.
Disaster due to Industrial Hazards and its effect on biodiversity
Pubali Dhar. Disaster and Its Management: Perspective and Future Approaches. ABC Publications.
Global Warming: Food security at stake
Climate Security: Perceptions, Challenges and Beyond. Academic Staff College, University of Calcutta.
NUTRIGRAM
E-book, 2022. Published by Udaynarayanpur Madhabilata Mahavidyalaya.
A selection of research by Prof. Dhar and collaborators.
Beni-Suef University Journal of Basic and Applied Sciences · 2025 · 14:118 · Review
Saswata Banerjee, Arpita Banerjee, Gautam Singhvi, Rajeev Taliyan and Pubali Dhar.
Co-authored by Prof. Pubali Dhar, this review examines mechanisms of multidrug resistance in cancer and research on dietary components and nutraceuticals as potential complementary approaches. It highlights the need for further focused evaluation.
Read publicationIndian Journal of Animal Health · 2025 · Volume 64(2), Special Issue · Review
A. Das, P. K. Nanda, D. Bhattacharya, P. Dhar and A. K. Das.
Co-authored by Prof. Pubali Dhar, this review explores plant-derived flavour components in fermented dairy products, including flavour formation, incorporation methods, sensory properties, product stability and future research directions.
Read publicationProbiotics and Antimicrobial Proteins · 2026 · Review
Sneha Dutta, Tapas K. Dutta, Pramod K. Nanda, Pubali Dhar, Arun K. Das and Arun K. Bhunia.
Co-authored by Prof. Pubali Dhar, this review examines the microbiota–gut–brain axis in aging and the potential role of probiotics in cognitive health. It highlights the strain-specific and context-dependent nature of probiotic effects.
Read publication Download open-access paper (PDF)Next Nanotechnology · Volume 10 · 2026 · 100809
Amrita Chakraborty, Niloy Chatterjee, Aatrayee Das, Sanjit Dey, Supratim Ghosh and Pubali Dhar.
Sesame oil nanoemulsions prepared using high-speed homogenization and solvent evaporation, with phospholipid and Tween 20 as emulsifiers. The study examines physical and oxidative stability and simulated gastrointestinal digestion.
Read publication Download open-access paper (PDF)Food Chemistry Advances · Volume 10 · 2026 · 101162
Trina Das, Sudip Baran Haiti, Debarchan Mondal, Kakoli Singh Sardar, Niloy Chatterjee and Pubali Dhar.
This study investigates enzymatic hydrolysis of mustard protein using papain, alcalase and pepsin. It evaluates solubility, emulsifying and foaming properties, antioxidant activity and in vitro ACE-inhibitory activity.
Read publicationFood Bioscience · 2024
Food Hydrocolloids for Health · Volume 4 · 2023 · 100143
Trina Das, Niloy Chatterjee, Amrita Chakraborty, Arpita Banerjee, Sudip Baran Haiti, Sriparna Datta, Helen Chattopadhyay and Pubali Dhar.
This study uses mustard protein isolate with Tween 20 to encapsulate gamma-oryzanol-rich rice bran oil in oil-in-water nanoemulsions prepared by high-pressure homogenisation. It evaluates storage and oxidative stability, simulated gastrointestinal digestion and cellular responses to oxidative stress.
Read publicationProf. Pubali Dhar received this award from the Oil Technologists’ Association of India for research contributions in lipid technology over the preceding three calendar years.
The plaque identifies it as the 2023 award. It was received at the association’s 77th and 78th Annual Convention and international conference on “Application of Oils and Fats in FMCG Sector,” held on 15–16 March 2024 at the National Agricultural Sciences Complex, New Delhi.
Prof. Dhar received this award in 2021 from the Physiological Society of India for work in Biochemistry and Nutrition.
Prof. Dhar received this award in 2016 from the Physiological Society of India for research in nutrition.
Prof. Dhar received this award in 2015 at the 70th Annual Convention of the Oil Technologists’ Association of India and the National Conference on “The Process and Product Developments for Better Economy Benefits of the Fats & Oils Industry,” held on 20–22 November 2015 at CSIR–Central Glass and Ceramic Research Institute, Kolkata, India.
Prof. Dhar received this award from the Oil Technologists’ Association of India and the Zaheer Foundation, New Delhi, for research contributions in lipid technology over the preceding three calendar years. The 2007 award was presented at the 63rd Annual Convention and National Seminar at CGCRI, Kolkata, on 29–30 November 2008.
Prof. Dhar received this award from the Physiological Society of India at Delhi University, Delhi, for the best research paper in Physiology and allied sciences during the calendar year.

Patent No. 606978 · Granted 26 October 2026
A granted patent on the green synthesis of silver nanoparticles using a non-invasive method.
Patentees: Niloy Chatterjee and Prof. Pubali Dhar
Application No. 202431101659 · Filed 21 December 2024
View the patent certificate (PDF)Patent No. 553136 · Granted 25 October 2024
A granted patent for preparing sesame oil nanoemulsions, using a low-energy method.
Patentees: Amrita Chakraborty, Niloy Chatterjee and Pubali Dhar
Application No. 202431006963 · Filed 1 February 2024
View the patent certificate (image)Bamboo oil nanoemulsion
Application No. 202431069814 · Filed 16 September 2024
The Patent Office, Government of India
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For research enquiries, please get in touch with the laboratory.
pdhomesc@caluniv.ac.inProf. Pubali Dhar: 9433122560 / 7003966709