Laboratory of Food Science
and Technology

University of Calcutta Kolkata, India

Food science,
with purpose.

Exploring functional foods and lipid nanotechnology at the Laboratory of Food Science and Technology.

Explore our research

Research rooted
in food.

Our work brings food science and nutrition together to investigate the properties and potential of food-derived materials.

Explore the department

Functional foods

Studying bioactive food components, proteins and peptides, and their potential applications in nutrition.

Lipid nanotechnology

Exploring lipid formulations and nanoemulsions for the delivery and study of bioactive compounds.

Food resources

Investigating useful ingredients from food and oil-industry materials, including plant proteins and dietary fibres.

Nutritional
sciences.

Prof. Pubali Dhar’s contributions connect lipid biotechnology, nano-nutrition and sustainable food resources.

Her research examines functional lipids and food-derived materials, with an emphasis on nutrient delivery, metabolic health and the use of agro-industrial by-products.

Functional lipids

Research on unconventional vegetable seed oils and marine resources explores their role in chronic metabolic disorders. Studies of conjugated linolenic acids (CLnA) from bitter gourd seed oil investigate mechanisms related to glucose regulation, inflammation and cholesterol metabolism.

Work on lutein, sesame lignans, plant sterols and diacylglycerol (DAG) cooking oils examines nutritional regulation, obesity, leptin dynamics and macronutrient absorption.

Nutrient delivery

To address limited bioavailability, chemical instability and autooxidation, the laboratory studies oil-in-water nanoemulsions and nanohydrogels using food-grade materials, including mustard and sesame protein isolates and phospholipids.

Studies of omega-3 fatty acid and sesame oil nano-formulations use experimental and flow-cytometric approaches to investigate cellular uptake, gastrointestinal bioaccessibility and mucosal barrier protection against foodborne pathogens. Further research explores potential applications in protein-energy malnutrition and gut-mucosal nutrient delivery for critically ill patients.

Sustainable food materials

The laboratory’s waste-to-wealth research investigates agro-industrial by-products as resources for useful food and biomaterial ingredients. Work with the oleaginous yeast Starmerella bombicola explores the conversion of refinery waste into sophorolipid biosurfactants.

Research on biogenic silver nanoparticles and green biopolymer films examines potential antimicrobial, food-preservation and active-packaging applications, including shelf-life stability.

Space nutrition

Ongoing work investigates growth, phenotypic plasticity and adaptive virulence in foodborne pathogens under simulated microgravity. This research seeks to inform future dietary interventions and food-preservation protocols for long-duration spaceflight and planetary missions.

Academic contribution

Prof. Dhar contributes to curriculum development through membership of university Boards of Studies. Her academic and research interests connect nutritional science with molecular approaches and the development of nano-nutraceutical delivery systems.

Research projects

Studies in food science, nutrition and nutraceutical delivery.

Principal investigator: Prof. Pubali Dhar

Dietary PUFAs

UGC Minor Research Project · 2002–2004

Studies on the protective role of dietary conjugated and non-conjugated polyunsaturated fatty acids (PUFAs) against coronary heart disease and diabetes mellitus.

The project compared the anti-inflammatory and antioxidant effects of conjugated alpha-eleostearic acid (α-ESA) with non-conjugated PUFAs. It examined the nutritional importance of conjugated linolenic acid (CLnA) in bitter gourd oil, contributing to knowledge in nutritional science.

Vegetable polyphenols

UGC Minor Research Project · 2006–2008

Studies on the antioxidative effects of polyphenols present in some vegetables in the presence of pesticides.

The project investigated how pesticide exposure affects vegetable polyphenol content and antioxidant potential, and examined the relationship between polyphenol content and antioxidant efficiency.

Its public-education aim was to improve awareness of polyphenol-rich vegetables and their potential role in protecting against oxidative stress associated with pesticide exposure.

Nanoemulsion development

Nano Research Centre, University of Calcutta · 2009–2011

Formulation and development of nanoemulsion.

The project explored nanoemulsion technology to improve the solubility, absorption and bioavailability of poorly water-soluble nutraceuticals. It also considered opportunities for commercialisation, product innovation and value-added formulations with market potential.

Edible flower extracts

UGC Major Research Project · 2010–2012

Studies on the antioxidative and antimicrobial activity of some edible flower extracts.

The project investigated the potential health-promoting properties of edible flowers of India, aiming to provide scientific evidence on their nutritional and medicinal value for nutritionists.

Bitter gourd oil CLnA

ICMR Research Project · 2011–2014

Studies on the antioxidative and immunomodulatory effects of conjugated linolenic acid (CLnA) from bitter gourd oil.

The project examined dose-dependent modulation of immune responses, including immune-cell activity and cytokine production. Its findings provided reference material for researchers in nutrition, biochemistry and immunology.

Maternal diet and milk lipids

UPE Project · 2011–2013

Diet and nutrition status of lactating mothers belonging to different socioeconomic classes residing in rural parts of Hooghly district, and their probable correlation with milk lipid profiles.

The study examined the relationship between maternal nutritional intake and breast-milk lipid profiles among Bengali mothers. It aimed to inform maternal and child health awareness and support public health policy.

Sesame seed protein

2012–2015

Supported by the Directorate of Vanaspati and Vegetable Oils and Fats, Ministry of Consumer Affairs, Government of India.

Studies on the antihypertensive and hypocholesterolemic effects of sesame seed protein.

The project investigated specific peptides or protein fractions associated with blood-pressure and cholesterol-lowering activities. Its outreach aim was to educate communities, healthcare professionals and nutritionists about the role of plant proteins in cardiovascular health.

Biogenic silver nanoparticles

UGC-DAE Consortium · 2016–2019

Application of green technology for the fabrication of biogenic flavonoid-coated silver nanoparticles.

The project investigated nanoparticle synthesis and potential applications in drug delivery, wound healing, antimicrobial formulations, biosensors and therapeutic products. Its focus included antimicrobial and antioxidant properties relevant to future infection-control and healthcare strategies.

PUFA-rich nanoemulsions

UPE-II · 2017–2020

Engineering PUFA-rich nanoemulsion systems for critical nutritional therapy.

The project focused on controlled and targeted nutrient release, with the aim of improving nutrient delivery in critical care nutrition.

Hypersensitivity nanocarriers

ICMR · 2019–2022

Systematizing novel lipid formulations as nanocarriers in targeting the molecular axis of hypersensitivity: For translational research.

The project investigated novel lipid-based nanocarriers with the aim of improving therapeutic efficacy. Its findings may inform further preclinical and clinical investigations into nanocarrier-based interventions for hypersensitivity disorders.

Nutrition and malnutrition

International Research Partnership, University of Saskatchewan, Canada · 2019–2022

Development of nutrient-rich oil-in-water nanoemulsion for diarrhoeal disease and associated malnutrition management in developing nations.

The project aimed to improve nutrient delivery and bioavailability to support the management of diarrhoeal disease and associated malnutrition. The developed system was explored for its potential to address nutrient deficiencies and improve nutritional status among vulnerable populations, especially children.

Sesame meal bioactive peptides

ICMR · 2022–2025

Identification and generation of immunomodulatory peptides from sesame seed oil meal: A novel radical approach in food value addition.

The project investigated the valorisation of sesame seed oil meal through the generation of bioactive peptides and examined their effects on immune-cell responses and cytokine activity. Its findings may support awareness of bioactive peptides and their potential role in immune health and preventive nutrition.

Ghee and cognitive health

Ministry of AYUSH · 2023–2026

Effect of ghee from indigenous cow milk on cognition and neuroprotection against Alzheimer’s disease.

The project investigates the potential neuroprotective effects of ghee prepared from indigenous cow milk using Ayurvedic methods, focusing on neurodegeneration and neuronal damage associated with Alzheimer’s disease. The research explores whether traditional dietary fats could inform future nutritional strategies for age-related cognitive decline.

Cooking oils and flavour

Palm Oil Council and OTAI · 2025–2026

Neurogastronomy insights: Comparing the effects of palm oil and alternative cooking oils on flavour perception and carcinogenic precursor formation.

The project examines interactions between food chemistry, sensory science and the neural processing of flavour. It aims to identify cooking-oil alternatives that combine desirable flavour with reduced formation of potentially harmful thermal degradation products, and to inform safer culinary practices.

The people
behind the work.

Research is a shared pursuit. Meet the principal investigator and the scholars working in the laboratory.

Principal investigator

Prof. Pubali Dhar

Professor, Department of Home Science
University of Calcutta

Prof. Dhar leads research in functional foods and lipid nanotechnology. She is also associated with the Centre for Research in Nanoscience and Nanotechnology.

Read the university profile

Research scholars

  • Debarchan Mondal
  • Kakoli Singh Sardar
  • Trina Das
  • Sudip Baran Haiti
  • Arnab Chakraborty
  • Sumana Patra

Doctoral scholars

Guided by Prof. Pubali Dhar · University of Calcutta

Our alumni

Dr. Arpita Banerjee

Dr. Banerjee completed her PhD at the Laboratory of Food Science and Technology, University of Calcutta. She is currently Head of the Department of Food and Nutrition at Sister Nivedita University, Kolkata.

A certificate presentation at a university ceremony

Dr. Amrita Chakraborty

Dr. Chakraborty completed her PhD in Physiology at the Laboratory of Food Science and Technology, University of Calcutta. She is currently an Assistant Professor in the West Bengal Educational Service.

A certificate presentation at a university ceremony

Dr. Madhusrita Das

Dr. Das completed her PhD in Nanoscience and Nanotechnology at the Laboratory of Food Science and Technology, University of Calcutta. She is currently an Assistant Professor in the Department of Biotechnology at Techno India University.

A certificate presentation at the University of Calcutta convocation

Dr. Shaswati Das

Dr. Das completed her PhD in Nanoscience and Nanotechnology at the Laboratory of Food Science and Technology, University of Calcutta. She currently works in the corporate sector in Bangalore.

A certificate presentation at the University of Calcutta convocation

Books and chapters

Selected publications

A selection of research by Prof. Dhar and collaborators.

View more on ORCID

Beni-Suef University Journal of Basic and Applied Sciences · 2025 · 14:118 · Review

The role of diet and nutraceuticals in the amelioration of multidrug resistance amongst cancer patients

Saswata Banerjee, Arpita Banerjee, Gautam Singhvi, Rajeev Taliyan and Pubali Dhar.

Co-authored by Prof. Pubali Dhar, this review examines mechanisms of multidrug resistance in cancer and research on dietary components and nutraceuticals as potential complementary approaches. It highlights the need for further focused evaluation.

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Indian Journal of Animal Health · 2025 · Volume 64(2), Special Issue · Review

Plant-based flavour components for fermented dairy products: A comprehensive review

A. Das, P. K. Nanda, D. Bhattacharya, P. Dhar and A. K. Das.

Co-authored by Prof. Pubali Dhar, this review explores plant-derived flavour components in fermented dairy products, including flavour formation, incorporation methods, sensory properties, product stability and future research directions.

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Probiotics and Antimicrobial Proteins · 2026 · Review

Paradigm Shift of Microbiota-gut-brain Axis During Aging: Potential Role of Probiotics to Improve Cognitive Decline

Sneha Dutta, Tapas K. Dutta, Pramod K. Nanda, Pubali Dhar, Arun K. Das and Arun K. Bhunia.

Co-authored by Prof. Pubali Dhar, this review examines the microbiota–gut–brain axis in aging and the potential role of probiotics in cognitive health. It highlights the strain-specific and context-dependent nature of probiotic effects.

Read publication Download open-access paper (PDF)

Next Nanotechnology · Volume 10 · 2026 · 100809

Toward sustainable food encapsulation: Eco-innovative and energy-efficient fabrication of phospholipid-stabilized nanoemulsions

Amrita Chakraborty, Niloy Chatterjee, Aatrayee Das, Sanjit Dey, Supratim Ghosh and Pubali Dhar.

Sesame oil nanoemulsions prepared using high-speed homogenization and solvent evaporation, with phospholipid and Tween 20 as emulsifiers. The study examines physical and oxidative stability and simulated gastrointestinal digestion.

Read publication Download open-access paper (PDF)

Food Chemistry Advances · Volume 10 · 2026 · 101162

Enzymatically enhanced mustard (Brassica nigra) protein hydrolysates as a next-generation plant-based pragmatic alternative: Functional and hypotensive efficacy

Trina Das, Sudip Baran Haiti, Debarchan Mondal, Kakoli Singh Sardar, Niloy Chatterjee and Pubali Dhar.

This study investigates enzymatic hydrolysis of mustard protein using papain, alcalase and pepsin. It evaluates solubility, emulsifying and foaming properties, antioxidant activity and in vitro ACE-inhibitory activity.

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Food Bioscience · 2024

Novel ACE inhibitory peptides from enzymatic hydrolysate of Channa punctata protein

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Food Hydrocolloids for Health · Volume 4 · 2023 · 100143

Fabrication of rice bran oil nanoemulsion and conventional emulsion with Mustard Protein Isolate as a novel excipient: Focus on shelf-life stability, lipid digestibility and cellular bioavailability

Trina Das, Niloy Chatterjee, Amrita Chakraborty, Arpita Banerjee, Sudip Baran Haiti, Sriparna Datta, Helen Chattopadhyay and Pubali Dhar.

This study uses mustard protein isolate with Tween 20 to encapsulate gamma-oryzanol-rich rice bran oil in oil-in-water nanoemulsions prepared by high-pressure homogenisation. It evaluates storage and oxidative stability, simulated gastrointestinal digestion and cellular responses to oxidative stress.

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Award and recognition

Dr. S. Husain Zaheer Memorial Award

Prof. Pubali Dhar received this award from the Oil Technologists’ Association of India for research contributions in lipid technology over the preceding three calendar years.

The plaque identifies it as the 2023 award. It was received at the association’s 77th and 78th Annual Convention and international conference on “Application of Oils and Fats in FMCG Sector,” held on 15–16 March 2024 at the National Agricultural Sciences Complex, New Delhi.

Dr. Chitralekha Mukherjee Memorial Award

Prof. Dhar received this award in 2021 from the Physiological Society of India for work in Biochemistry and Nutrition.

Mrs. Sakuntala Dasgupta Memorial Award

Prof. Dhar received this award in 2016 from the Physiological Society of India for research in nutrition.

Dr. S. D. Thirumala Rao Memorial Award

Prof. Dhar received this award in 2015 at the 70th Annual Convention of the Oil Technologists’ Association of India and the National Conference on “The Process and Product Developments for Better Economy Benefits of the Fats & Oils Industry,” held on 20–22 November 2015 at CSIR–Central Glass and Ceramic Research Institute, Kolkata, India.

Dr. S. Hussain Zaheer Memorial Award — 2007

Prof. Dhar received this award from the Oil Technologists’ Association of India and the Zaheer Foundation, New Delhi, for research contributions in lipid technology over the preceding three calendar years. The 2007 award was presented at the 63rd Annual Convention and National Seminar at CGCRI, Kolkata, on 29–30 November 2008.

P. B. Sen Memorial Award — 1999

Prof. Dhar received this award from the Physiological Society of India at Delhi University, Delhi, for the best research paper in Physiology and allied sciences during the calendar year.

Dr. S. Husain Zaheer Memorial Award plaque presented to Prof. Pubali Dhar

Patents

Patent No. 606978 · Granted 26 October 2026

Green synthesis of silver nanoparticles in non-invasive method

A granted patent on the green synthesis of silver nanoparticles using a non-invasive method.

Patentees: Niloy Chatterjee and Prof. Pubali Dhar

Application No. 202431101659 · Filed 21 December 2024

View the patent certificate (PDF)

Sesame oil nanoemulsion

Patent No. 553136 · Granted 25 October 2024

Method of preparation of a novel sesame oil nano emulsion formulation

A granted patent for preparing sesame oil nanoemulsions, using a low-energy method.

Patentees: Amrita Chakraborty, Niloy Chatterjee and Pubali Dhar

Application No. 202431006963 · Filed 1 February 2024

View the patent certificate (image)

Filed patent application

Bamboo oil nanoemulsion

Method of preparation of a novel bamboo oil nano emulsion formulation and product thereof

Application No. 202431069814 · Filed 16 September 2024

The Patent Office, Government of India

Life in the lab.

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Let’s connect.

For research enquiries, please get in touch with the laboratory.

Prof. Pubali Dhar: 9433122560 / 7003966709

Laboratory of Food Science and Technology
University of Calcutta
20B Judges Court Road
Kolkata 700027, India